Question:
What is Coenzyme Q10?
Answer:

Coenzyme Q10, or ubiquinone, is a compound with an essential role in mitochondrial electron transport, making it a fundamental part of cellular energy production.

Coenzyme Q10 is also an antioxidant. Its ability to quench free radicals helps maintain the structural integrity and stability of cell membranes (including intracellular membranes). It is also capable of improving oxidation resistance of low-density lipoprotein (LDL) cholesterol. Additional evidence suggests that Coenzyme Q10 uses its antioxidant capabilities to regenerate vitamin E.

CoQ10's other name, ubiquinone, signifies its ubiquitous (widespread) distribution in the human body. Highest levels of Coenzyme Q10 are found in the heart, liver, kidney, and pancreas.

CoQ10 supplementation has therapeutic benefits for several diseases. Some of the best-documented effects involve cases of heart failure, ischemic heart disease, certain muscular dystrophies, hypertension, and periodontal disease.

CoQ10 is synthesized in all cells of the body. It is also absorbed from food. Major sources of dietary CoQ10 include meats, fish, and vegetable oils (particularly soybean, sesame, and rapeseed oils). Vegetables are generally low in CoQ10, with the exception of spinach and broccoli.

As aging occurs, the body's ability to synthesize CoQ10 diminishes significantly. Deficiencies may also result from reduced assimilation from dietary sources.

Coenzyme Q10 supplements are generally considered safe and are best absorbed by the body when taken with foods. The usual maintenance dose is 10-30 mg per day, although higher doses are used therapeutically for the treatment of heart and blood vessel disease.